Cargando…

HPV16 Oncoproteins Promote Cervical Cancer Invasiveness by Upregulating Specific Matrix Metalloproteinases

Production of matrix metalloproteinases (MMPs) for degradation of extracellular matrix is a vital step in cancer metastasis. We investigated the effects of HPV16 oncoproteins (16E6, 16E6*I and 16E7), either individually or combined, on the transcription of 7 MMPs implicated in cervical cancer invasi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaewprag, Jittranan, Umnajvijit, Wareerat, Ngamkham, Jarunya, Ponglikitmongkol, Mathurose
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742460/ https://www.ncbi.nlm.nih.gov/pubmed/23967226 http://dx.doi.org/10.1371/journal.pone.0071611

Ejemplares similares

Differential localization of HPV16 E6 splice products with E6-associated protein
por: Vaeteewoottacharn, Kulthida, et al.
Publicado: (2005)

Post-Translational Control of IL-1β via the Human Papillomavirus Type 16 E6 Oncoprotein: A Novel Mechanism of Innate Immune Escape Mediated by the E3-Ubiquitin Ligase E6-AP and p53
por: Niebler, Martina, et al.
Publicado: (2013)

IRF-1 Inhibits Angiogenic Activity of HPV16 E6 Oncoprotein in Cervical Cancer
por: Rho, Seung Bae, et al.
Publicado: (2020)

Major single nucleotide polymorphisms in polypoidal choroidal vasculopathy: a comparative analysis between Thai and other Asian populations
por: Chantaren, Patchima, et al.
Publicado: (2012)

CRISPR Cas9-mediated ablation of pyruvate carboxylase gene in colon cancer cell line HT-29 inhibits growth and migration, induces apoptosis and increases sensitivity to 5-fluorouracil and glutaminase inhibitor
por: Ngamkham, Jarunya, et al.
Publicado: (2022)

Novel Affibody Molecules Targeting the HPV16 E6 Oncoprotein Inhibited the Proliferation of Cervical Cancer Cells
por: Zhu, Jinshun, et al.
Publicado: (2021)

HPV16 E7 oncoprotein test as a triage strategy for HPV16-positive women in cervical cancer screening: long-term follow-up outcome
por: Wang, Xinmei, et al.
Publicado: (2023)

Uneven distribution of HPV 16 E6 prototype and variant (L83V) oncoprotein in cervical neoplastic lesions
por: Andersson, S, et al.
Publicado: (2000)

HPV16 Oncoproteins Induce MMPs/RECK-TIMP-2 Imbalance in Primary Keratinocytes: Possible Implications in Cervical Carcinogenesis
por: Cardeal, Laura Beatriz da Silva, et al.
Publicado: (2012)

Non-Metabolic Functions of PKM2 Contribute to Cervical Cancer Cell Proliferation Induced by the HPV16 E7 Oncoprotein
por: Lee, Seoung-Ae, et al.
Publicado: (2021)

Anti-HPV16 oncoproteins siRNA therapy for cervical cancer using a novel transdermal peptide PKU12
por: Deng, Yan, et al.
Publicado: (2023)

Manipulation of Epithelial Differentiation by HPV Oncoproteins
por: White, Elizabeth A.
Publicado: (2019)

Effects of human papillomavirus (HPV) type 16 oncoproteins on the expression of involucrin in human keratinocytes
por: Gyöngyösi, Eszter, et al.
Publicado: (2012)

An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein
por: Belyaeva, Tamara A., et al.
Publicado: (2014)

HPV16 AND EXPRESSION OF PROTEIN P16(INK4A) AND E7 ONCOPROTEIN IN COLORECTAL CARCINOMA
por: PICANÇO-JUNIOR, Olavo Magalhães, et al.
Publicado: (2022)

RIPOR2 Expression Decreased by HPV-16 E6 and E7 Oncoproteins: An Opportunity in the Search for Prognostic Biomarkers in Cervical Cancer
por: Olmedo-Nieva, Leslie, et al.
Publicado: (2022)

Diarylheptanoid Phytoestrogens Isolated from the Medicinal Plant Curcuma comosa: Biologic Actions in Vitro and in Vivo Indicate Estrogen Receptor–Dependent Mechanisms
por: Winuthayanon, Wipawee, et al.
Publicado: (2009)

Molecular Landscape and Computational Screening of the Natural inhibitors against HPV16 E6 Oncoprotein
por: Juneja, Tanzil, et al.
Publicado: (2021)

In silico prediction of structural changes in human papillomavirus type 16 (HPV16) E6 oncoprotein and its variants
por: Rodríguez-Ruiz, Hugo Alberto, et al.
Publicado: (2019)

Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9
por: Wang, Caimei, et al.
Publicado: (2022)

The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression
por: He, Chunbo, et al.
Publicado: (2015)

Immunohistochemical Detection of Human Papillomavirus 16 E7 Oncoprotein in Cervical Lesions
por: Zhu, Jiang, et al.
Publicado: (2021)

Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis
por: Kumar, Satish, et al.
Publicado: (2014)

A comprehensive in silico analysis for identification of therapeutic epitopes in HPV16, 18, 31 and 45 oncoproteins
por: Panahi, Heidar Ali, et al.
Publicado: (2018)

Serum HPV16 E7 Oncoprotein Is a Recurrence Marker of Oropharyngeal Squamous Cell Carcinomas
por: Oton-Gonzalez, Lucia, et al.
Publicado: (2021)

Matrix metalloproteinase-induced cervical extracellular matrix remodelling in pregnancy and cervical cancer
por: Amabebe, Emmanuel, et al.
Publicado: (2022)

Risk stratification of HPV 16 DNA methylation combined with E6 oncoprotein in cervical cancer screening: a 10-year prospective cohort study
por: Dong, Li, et al.
Publicado: (2020)

Metalloproteinase meprin α regulates migration and invasion of human hepatocarcinoma cells and is a mediator of the oncoprotein Reptin
por: Breig, Osman, et al.
Publicado: (2016)

Mechanisms of cartilage matrix turnover: synergistic interactions of proinflammatory cytokines with oncostatin M in upregulating matrix metalloproteinases and ADAMTS metalloproteinases
por: Cawston, TE, et al.
Publicado: (2005)

Epigenetics of Epileptogenesis-Evoked Upregulation of Matrix Metalloproteinase-9 in Hippocampus
por: Zybura-Broda, Katarzyna, et al.
Publicado: (2016)

Epigenetic hypomethylation and upregulation of matrix metalloproteinase 9 in Kawasaki disease
por: Kuo, Ho-Chang, et al.
Publicado: (2017)

An RNA Aptamer Provides a Novel Approach for the Induction of Apoptosis by Targeting the HPV16 E7 Oncoprotein
por: Nicol, Clare, et al.
Publicado: (2013)

The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo
por: Cortés-Malagón, Enoc Mariano, et al.
Publicado: (2017)

Preparation, Characterization and Diagnostic Valuation of Two Novel Anti-HPV16 E7 Oncoprotein Monoclonal Antibodies
por: Hu, Renjian, et al.
Publicado: (2020)

HPV16 E6 Promotes the Progression of HPV Infection-Associated Cervical Cancer by Upregulating Glucose-6-Phosphate Dehydrogenase Expression
por: Chang, Ye-Fei, et al.
Publicado: (2021)

Early synergistic interactions between the HPV16-E7 oncoprotein and 17β-oestradiol for repressing the expression of Granzyme B in a cervical cancer model
por: Munguía-Moreno, J. Antonio, et al.
Publicado: (2018)

Development and validation of a multiplex immunoassay for the simultaneous quantification of type-specific IgG antibodies to E6/E7 oncoproteins of HPV16 and HPV18
por: Layman, Hans, et al.
Publicado: (2020)

Hypoxia inducible factor-1 alpha expression is increased in infected positive HPV16 DNA oral squamous cell carcinoma and positively associated with HPV16 E7 oncoprotein
por: Rodolico, Vito, et al.
Publicado: (2011)

Bridging Links between Long Noncoding RNA HOTAIR and HPV Oncoprotein E7 in Cervical Cancer Pathogenesis
por: Sharma, Sweta, et al.
Publicado: (2015)

Resveratrol and Pterostilbene Exhibit Anticancer Properties Involving the Downregulation of HPV Oncoprotein E6 in Cervical Cancer Cells
por: Chatterjee, Kaushiki, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_l5kkjoe66mi7p8rthhev5k52r7