Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: Relevance to lung cancer

Cytoskeletal and focal adhesion abnormalities are observed in several types of cancer, including lung cancer. We have previously reported that paxillin (PXN) was mutated, amplified, and overexpressed in a significant number of lung cancer patient samples, that PXN protein was upregulated in more adv...

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Detalles Bibliográficos
Autores principales: Kawada, Ichiro, Hasina, Rifat, Lennon, Frances E, Bindokas, Vytautas P, Usatyuk, Peter, Tan, Yi-Hung C, Krishnaswamy, Soundararajan, Arif, Qudsia, Carey, George, Hseu, Robyn D, Robinson, Matthew, Tretiakova, Maria, Brand, Toni M, Iida, Mari, Ferguson, Mark K, Wheeler, Deric L, Husain, Aliya N, Natarajan, Viswanathan, Vokes, Everett E, Singleton, Patrick A, Salgia, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742497/
https://www.ncbi.nlm.nih.gov/pubmed/23792636
http://dx.doi.org/10.4161/cbt.25091

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