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Prolonged Minocycline Treatment Impairs Motor Neuronal Survival and Glial Function in Organotypic Rat Spinal Cord Cultures

BACKGROUND: Minocycline, a second-generation tetracycline antibiotic, exhibits anti-inflammatory and neuroprotective effects in various experimental models of neurological diseases, such as stroke, Alzheimer’s disease, amyotrophic lateral sclerosis and spinal cord injury. However, conflicting result...

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Detalles Bibliográficos
Autores principales:	Pinkernelle, Josephine, Fansa, Hisham, Ebmeyer, Uwe, Keilhoff, Gerburg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742532/ https://www.ncbi.nlm.nih.gov/pubmed/23967343 http://dx.doi.org/10.1371/journal.pone.0073422

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