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Structural Basis for the Interaction of the Adaptor Protein Grb14 with Activated Ras
Grb14, a member of the Grb7-10-14 family of cytoplasmic adaptor proteins, is a tissue-specific negative regulator of insulin signaling. Grb7-10-14 contain several signaling modules, including a Ras-associating (RA) domain, a pleckstrin-homology (PH) domain, a family-specific BPS (between PH and SH2)...
Autores principales: | Qamra, Rohini, Hubbard, Stevan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742580/ https://www.ncbi.nlm.nih.gov/pubmed/23967305 http://dx.doi.org/10.1371/journal.pone.0072473 |
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