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2-Methoxyestradiol Induces Mitotic Arrest, Apoptosis, and Synergistic Cytotoxicity with Arsenic Trioxide in Human Urothelial Carcinoma Cells
2-Methoxyestradiol (2-ME), an endogenous derivative of 17β-estradiol, has been reported to elicit antiproliferative responses in various tumors. In this study, we investigated the effects of 2-ME on cell viability, proliferation, cell cycle, and apoptosis in human urothelial carcinoma (UC) cell line...
Autores principales: | Kuo, Kuan-Lin, Lin, Wei-Chou, Ho, I-Lin, Chang, Hong-Chiang, Lee, Ping-Yi, Chung, Yuan-Ting, Hsieh, Ju-Ton, Pu, Yeong-Shiau, Shi, Chung-Sheng, Huang, Kuo-How |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742604/ https://www.ncbi.nlm.nih.gov/pubmed/23967052 http://dx.doi.org/10.1371/journal.pone.0068703 |
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