Cargando…
Synucleins Antagonize Endoplasmic Reticulum Function to Modulate Dopamine Transporter Trafficking
Synaptic re-uptake of dopamine is dependent on the dopamine transporter (DAT), which is regulated by its distribution to the cell surface. DAT trafficking is modulated by the Parkinson's disease-linked protein alpha-synuclein, but the contribution of synuclein family members beta-synuclein and...
Autores principales: | Oaks, Adam W., Marsh-Armstrong, Nicholas, Jones, Jessica M., Credle, Joel J., Sidhu, Anita |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742698/ https://www.ncbi.nlm.nih.gov/pubmed/23967127 http://dx.doi.org/10.1371/journal.pone.0070872 |
Ejemplares similares
-
Parallel mechanisms for direct and indirect membrane protein trafficking by synucleins
por: Oaks, Adam W, et al.
Publicado: (2013) -
Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease
por: Kaul, Tiffany, et al.
Publicado: (2011) -
Tauopathic Changes in the Striatum of A53T α-Synuclein Mutant Mouse Model of Parkinson's Disease
por: Wills, Jonathan, et al.
Publicado: (2011) -
α-Synuclein Delays Endoplasmic Reticulum (ER)-to-Golgi Transport in Mammalian Cells by Antagonizing ER/Golgi SNAREs
por: Thayanidhi, Nandhakumar, et al.
Publicado: (2010) -
Correction: Paraquat, but Not Maneb, Induces Synucleinopathy and Tauopathy in Striata of Mice through Inhibition of Proteasomal and Autophagic Pathways
por: Wills, Jonathan, et al.
Publicado: (2012)