Transcription Factor TFAP2C Regulates Major Programs Required for Murine Fetal Germ Cell Maintenance and Haploinsufficiency Predisposes to Teratomas in Male Mice

Maintenance and maturation of primordial germ cells is controlled by complex genetic and epigenetic cascades, and disturbances in this network lead to either infertility or malignant aberration. Transcription factor TFAP2C has been described to be essential for primordial germ cell maintenance and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Schemmer, Jana, Araúzo-Bravo, Marcos J., Haas, Natalie, Schäfer, Sabine, Weber, Susanne N., Becker, Astrid, Eckert, Dawid, Zimmer, Andreas, Nettersheim, Daniel, Schorle, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742748/
https://www.ncbi.nlm.nih.gov/pubmed/23967156
http://dx.doi.org/10.1371/journal.pone.0071113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742748/
https://www.ncbi.nlm.nih.gov/pubmed/23967156
http://dx.doi.org/10.1371/journal.pone.0071113

Ejemplares similares