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Increased Corneal Epithelial Turnover Contributes to Abnormal Homeostasis in the Pax6(+/−) Mouse Model of Aniridia

We aimed to test previous predictions that limbal epithelial stem cells (LESCs) are quantitatively deficient or qualitatively defective in Pax6(+/−) mice and decline with age in wild-type (WT) mice. Consistent with previous studies, corneal epithelial stripe patterns coarsened with age in WT mosaics...

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Detalles Bibliográficos
Autores principales:	Douvaras, Panagiotis, Mort, Richard L., Edwards, Dominic, Ramaesh, Kanna, Dhillon, Baljean, Morley, Steven D., Hill, Robert E., West, John D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742784/ https://www.ncbi.nlm.nih.gov/pubmed/23967157 http://dx.doi.org/10.1371/journal.pone.0071117

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