Cargando…

Expression of p53, epidermal growth factor receptor, Ki-67 and O(6)-methylguanine-DNA methyltransferase in human gliomas

The present study aimed to evaluate the expression of p53, Ki-67, epidermal growth factor receptor (EGFR) and O(6)-methylguanine-DNA methyltransferase (MGMT), and to analyze the correlation between their expression and the histological grade of the tumors in 152 patients with gliomas. The tumors wer...

Descripción completa

Detalles Bibliográficos
Autores principales:	HU, XINHUA, MIAO, WEI, ZOU, YUANJIE, ZHANG, WENBIN, ZHANG, YANSONG, LIU, HONGYI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742817/ https://www.ncbi.nlm.nih.gov/pubmed/23946790 http://dx.doi.org/10.3892/ol.2013.1317

Ejemplares similares

Evaluation of prognostic utility of Ki-67, P53, and O-6-methylguanine-DNA methyltransferase expression in pituitary tumors
por: Das, Chhanda, et al.
Publicado: (2019)

O(6)-Methylguanine-DNA Methyltransferase (MGMT): Challenges and New Opportunities in Glioma Chemotherapy
por: Yu, Wei, et al.
Publicado: (2020)

O(6)-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas
por: Fan, C-H, et al.
Publicado: (2013)

Prognostic value of O(6)-methylguanine-DNA methyltransferase methylation in isocitrate dehydrogenase mutant gliomas
por: Lam, Keng, et al.
Publicado: (2022)

O(6)-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies
por: Sasai, Ken, et al.
Publicado: (2007)

Erratum to: Prognostic value of O(6)-methylguanine-DNA methyltransferase methylation in isocitrate dehydrogenase mutant gliomas
Publicado: (2022)

Radiomic prediction models for the level of Ki-67 and p53 in glioma
por: Sun, Xiaojun, et al.
Publicado: (2020)

High-dose radiotherapy in newly diagnosed low-grade gliomas with nonmethylated O(6)-methylguanine-DNA methyltransferase
por: Liu, Yanwei, et al.
Publicado: (2021)

The role of direct DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) in high grade malignant glioma
por: Manoj, M Jeru, et al.
Publicado: (2014)

Immunohistochemical Assessment of O(6)-Methylguanine-DNA Methyltransferase (MGMT) and Its Relationship with p53 Expression in Endometrial Cancers
por: Lee, Kyung Eun
Publicado: (2013)

O6-methylguanine-DNA methyltransferase activities in biopsies of human melanoma tumours.
por: Egyházi, S., et al.
Publicado: (1995)

Regulation of O6-methylguanine-DNA methyltransferase by methionine in human tumour cells.
por: Kokkinakis, D. M., et al.
Publicado: (1997)

O(6)-methylguanine-DNA methyltransferase in equine sarcoids: molecular and epigenetic analysis
por: Altamura, Gennaro, et al.
Publicado: (2012)

Regulation of expression of O(6)-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review)
por: CABRINI, GIULIO, et al.
Publicado: (2015)

miR-29c contribute to glioma cells temozolomide sensitivity by targeting O(6)-methylguanine-DNA methyltransferases indirectly
por: Xiao, Songhua, et al.
Publicado: (2016)

Brain Tumor Radiogenomic Classification of O(6)-Methylguanine-DNA Methyltransferase Promoter Methylation in Malignant Gliomas-Based Transfer Learning
por: Sakly, Houneida, et al.
Publicado: (2023)

O(6)‐Methylguanine‐DNA Methyltransferase (MGMT) as a Determinant of Resistance to Camptothecin Derivatives
por: Okamoto, Ryo, et al.
Publicado: (2002)

Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O(6)-methylguanine-DNA methyltransferase with a double arm hybrid molecule
por: Rupp, Martin, et al.
Publicado: (2018)

O(6)-Methylguanine-DNA Methyltransferase (MGMT) mRNA Expression Predicts Outcome in Malignant Glioma Independent of MGMT Promoter Methylation
por: Kreth, Simone, et al.
Publicado: (2011)

O(6)-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma
por: Bobola, Michael S., et al.
Publicado: (2014)

The diagnostic value of ADC histogram and direct ADC measurements for coexisting isocitrate dehydrogenase mutation and O6-methylguanine-DNA methyltransferase promoter methylation in glioma
por: Xie, Zhiyan, et al.
Publicado: (2023)

O-6-Methylguanine-DNA methyltransferase expression is associated with pituitary adenoma tumor recurrence: a systematic meta-analysis
por: Dai, Congxin, et al.
Publicado: (2017)

Inhibition of O(6)-methylguanine-DNA methyltransferase by an alkyltransferase-like protein from Escherichia coli
por: Pearson, Steven J., et al.
Publicado: (2005)

Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival
por: Robinson, C G, et al.
Publicado: (2010)

Atomic Insight into the Altered O(6)-Methylguanine-DNA Methyltransferase Protein Architecture in Gastric Cancer
por: Chikan, Naveed Anjum, et al.
Publicado: (2015)

miR-130a can predict response to temozolomide in patients with glioblastoma multiforme, independently of O6-methylguanine-DNA methyltransferase
por: Chen, Huiyuan, et al.
Publicado: (2015)

Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumours.
por: Jaros, E., et al.
Publicado: (1992)

Inactivation of O(6)-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers
por: Bae, S I, et al.
Publicado: (2002)

O(6)-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma
por: Ma, S, et al.
Publicado: (2003)

O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma.
por: Middleton, M. R., et al.
Publicado: (1998)

O-6-methylguanine DNA methyltransferase is a favorable biomarker with proliferation suppressive potential in Breast Cancer
por: Lin, Danxia, et al.
Publicado: (2020)

Phenotypic selection through cell death: stochastic modelling of O-6-methylguanine-DNA methyltransferase dynamics
por: Lasri, Ayoub, et al.
Publicado: (2020)

O(6)-methylguanine DNA methyltransferase and glucose transporter 2 in foregut and hindgut gastrointestinal neuroendocrine neoplasms
por: Watanabe, Hirofumi, et al.
Publicado: (2020)

Autophagy deficiency downregulates O(6)methylguanine-DNA methyltransferase and increases chemosensitivity of liver cancer cells
por: Hou, Xiaojuan, et al.
Publicado: (2021)

Roles of the hydroxy group of tyrosine in crystal structures of Sulfurisphaera tokodaii O (6)-methylguanine-DNA methyltransferase
por: Kikuchi, Makiko, et al.
Publicado: (2021)

O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib
por: Watson, A J, et al.
Publicado: (2009)

Induced Synthesis of O(6)‐Methylguanine‐DNA Methyltransferase in Rat Hepatoma Cells Exposed to DNA‐damaging Agents
por: Fukuhara, Masao, et al.
Publicado: (1992)

Enhanced Anti-Tumor Effect of Zoledronic Acid Combined with Temozolomide against Human Malignant Glioma Cell Expressing O(6)-Methylguanine DNA Methyltransferase
por: Fukai, Junya, et al.
Publicado: (2014)

FoxD2-AS1 is a prognostic factor in glioma and promotes temozolomide resistance in a O(6)-methylguanine-DNA methyltransferase-dependent manner
por: Shangguan, Wenbing, et al.
Publicado: (2019)

Significance of p53 and ki-67 expression in prostate cancer
por: Verma, Renuka, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dmu07lp0piqvtkhi0jm286bq70