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P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy

BACKGROUND: Mutations in the p53 gene are amongst the most frequent aberrations seen in human cancer. Our objective was to characterize the clinical characteristics associated with p53 mutation in patients with advanced cancer. METHODS: We retrospectively reviewed and analyzed the clinical features...

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Detalles Bibliográficos
Autores principales: Said, Rabih, Hong, David S., Warneke, Carla L., Lee, J. Jack, Wheler, Jennifer J., Janku, Filip, Naing, Aung, Falchook, Gerald S., Fu, Siqing, Piha-Paul, Sarina, Tsimberidou, Apostolia M., Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742831/
https://www.ncbi.nlm.nih.gov/pubmed/23670029