A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

Mostrar otras versiones (1)

In contrast to its close homolog CDK4, the cell cycle kinase CDK6 is expressed at high levels in lymphoid malignancies. In a model for p185(BCR-ABL+) B-acute lymphoid leukemia, we show that CDK6 is part of a transcription complex that induces the expression of the tumor suppressor p16(INK4a) and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kollmann, Karoline, Heller, Gerwin, Schneckenleithner, Christine, Warsch, Wolfgang, Scheicher, Ruth, Ott, Rene G., Schäfer, Markus, Fajmann, Sabine, Schlederer, Michaela, Schiefer, Ana-Iris, Reichart, Ursula, Mayerhofer, Matthias, Hoeller, Christoph, Zöchbauer-Müller, Sabine, Kerjaschki, Dontscho, Bock, Christoph, Kenner, Lukas, Hoefler, Gerald, Freissmuth, Michael, Green, Anthony R., Moriggl, Richard, Busslinger, Meinrad, Malumbres, Marcos, Sexl, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743049/
https://www.ncbi.nlm.nih.gov/pubmed/23948297
http://dx.doi.org/10.1016/j.ccr.2013.07.012

Ejemplares similares

Ejemplares similares