Use of Octeriotide in the Management of Neonatal Chylothorax Secondary to Repair of Congenital Diaphragmatic Hernia: A Report of Two Cases and Review of Literature

Chylothorax, a known complication of surgery for Congenital Diaphragmatic hernia, can sometimes be resistant to treat. Octeriotide (Somatostatin analogue) can be useful in this situation. However, the dose and schedule of Octeriotide therapy in neonates is not well established. We report two cases o...

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Autores principales: Jarir, Rawia A., Rahman, Sajjad ur, Bassiouny, Ibrahim El Sayed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743138/
https://www.ncbi.nlm.nih.gov/pubmed/24027698
http://dx.doi.org/10.4103/2249-4847.96767
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author Jarir, Rawia A.
Rahman, Sajjad ur
Bassiouny, Ibrahim El Sayed
author_facet Jarir, Rawia A.
Rahman, Sajjad ur
Bassiouny, Ibrahim El Sayed
author_sort Jarir, Rawia A.
collection PubMed
description Chylothorax, a known complication of surgery for Congenital Diaphragmatic hernia, can sometimes be resistant to treat. Octeriotide (Somatostatin analogue) can be useful in this situation. However, the dose and schedule of Octeriotide therapy in neonates is not well established. We report two cases of resistant chylothorax following surgery for congenital diaphragmatic hernia which were successfully managed by using an escalating infusion of octeriotide. The literature on the subject is also reviewed.
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spelling pubmed-37431382013-09-11 Use of Octeriotide in the Management of Neonatal Chylothorax Secondary to Repair of Congenital Diaphragmatic Hernia: A Report of Two Cases and Review of Literature Jarir, Rawia A. Rahman, Sajjad ur Bassiouny, Ibrahim El Sayed J Clin Neonatol Case Report Chylothorax, a known complication of surgery for Congenital Diaphragmatic hernia, can sometimes be resistant to treat. Octeriotide (Somatostatin analogue) can be useful in this situation. However, the dose and schedule of Octeriotide therapy in neonates is not well established. We report two cases of resistant chylothorax following surgery for congenital diaphragmatic hernia which were successfully managed by using an escalating infusion of octeriotide. The literature on the subject is also reviewed. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3743138/ /pubmed/24027698 http://dx.doi.org/10.4103/2249-4847.96767 Text en Copyright: © Journal of Clinical Neonatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jarir, Rawia A.
Rahman, Sajjad ur
Bassiouny, Ibrahim El Sayed
Use of Octeriotide in the Management of Neonatal Chylothorax Secondary to Repair of Congenital Diaphragmatic Hernia: A Report of Two Cases and Review of Literature
title Use of Octeriotide in the Management of Neonatal Chylothorax Secondary to Repair of Congenital Diaphragmatic Hernia: A Report of Two Cases and Review of Literature
title_full Use of Octeriotide in the Management of Neonatal Chylothorax Secondary to Repair of Congenital Diaphragmatic Hernia: A Report of Two Cases and Review of Literature
title_fullStr Use of Octeriotide in the Management of Neonatal Chylothorax Secondary to Repair of Congenital Diaphragmatic Hernia: A Report of Two Cases and Review of Literature
title_full_unstemmed Use of Octeriotide in the Management of Neonatal Chylothorax Secondary to Repair of Congenital Diaphragmatic Hernia: A Report of Two Cases and Review of Literature
title_short Use of Octeriotide in the Management of Neonatal Chylothorax Secondary to Repair of Congenital Diaphragmatic Hernia: A Report of Two Cases and Review of Literature
title_sort use of octeriotide in the management of neonatal chylothorax secondary to repair of congenital diaphragmatic hernia: a report of two cases and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743138/
https://www.ncbi.nlm.nih.gov/pubmed/24027698
http://dx.doi.org/10.4103/2249-4847.96767
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