Disruption of Hydrogen Bonds between Major Histocompatibility Complex Class II and the Peptide N-Terminus Is Not Sufficient to Form a Human Leukocyte Antigen-DM Receptive State of Major Histocompatibility Complex Class II

Peptide presentation by MHC class II is of critical importance to the function of CD4+ T cells. HLA-DM resides in the endosomal pathway and edits the peptide repertoire of newly synthesized MHC class II molecules before they are exported to the cell surface. HLA-DM ensures MHC class II molecules bin...

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Detalles Bibliográficos
Autores principales: Schulze, Monika-Sarah E. D., Anders, Anne-Kathrin, Sethi, Dhruv K., Call, Melissa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743349/
https://www.ncbi.nlm.nih.gov/pubmed/23976922
http://dx.doi.org/10.1371/journal.pone.0069228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743349/
https://www.ncbi.nlm.nih.gov/pubmed/23976922
http://dx.doi.org/10.1371/journal.pone.0069228

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