Pituitary oncocytoma presenting as Cushing's disease

A 19-year-old girl presented with classical features of Cushing's syndrome. Endocrinal evaluation was consistent with pituitary source of ACTH; but imaging showed normal pituitary. Bilateral inferior petrosal sinus sampling confirmed the diagnosis. A successful remission was achieved after aden...

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Detalles Bibliográficos
Autores principales: Garg, M.K., Bharwaj, Reena, Pathak, H.C., Kharb, Sandeep, Gundgurthi, Abhay, Pandit, Aditi, Brar, K.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743387/
https://www.ncbi.nlm.nih.gov/pubmed/23961503
http://dx.doi.org/10.4103/2230-8210.113778
Descripción
Sumario:A 19-year-old girl presented with classical features of Cushing's syndrome. Endocrinal evaluation was consistent with pituitary source of ACTH; but imaging showed normal pituitary. Bilateral inferior petrosal sinus sampling confirmed the diagnosis. A successful remission was achieved after adenomectomy by transphenoidal route. Histopathological examination was consistent with pituitary oncocytoma and immunohistochemistry was positive for synaptophysin, chromogranin, neuron specific enolase, S-100, ACTH, prolactin, and GH.

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