Vaginal concentrations of lactic acid potently inactivate HIV

OBJECTIVES: When Lactobacillus spp. dominate the vaginal microbiota of women of reproductive age they acidify the vagina to pH <4.0 by producing ∼1% lactic acid in a nearly racemic mixture of d- and l-isomers. We determined the HIV virucidal activity of racemic lactic acid, and its d- and l-isome...

Descripción completa

Detalles Bibliográficos
Autores principales: Aldunate, Muriel, Tyssen, David, Johnson, Adam, Zakir, Tasnim, Sonza, Secondo, Moench, Thomas, Cone, Richard, Tachedjian, Gilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743514/
https://www.ncbi.nlm.nih.gov/pubmed/23657804
http://dx.doi.org/10.1093/jac/dkt156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743514/
https://www.ncbi.nlm.nih.gov/pubmed/23657804
http://dx.doi.org/10.1093/jac/dkt156

Ejemplares similares