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Vaginal concentrations of lactic acid potently inactivate HIV
OBJECTIVES: When Lactobacillus spp. dominate the vaginal microbiota of women of reproductive age they acidify the vagina to pH <4.0 by producing ∼1% lactic acid in a nearly racemic mixture of d- and l-isomers. We determined the HIV virucidal activity of racemic lactic acid, and its d- and l-isome...
Autores principales: | Aldunate, Muriel, Tyssen, David, Johnson, Adam, Zakir, Tasnim, Sonza, Secondo, Moench, Thomas, Cone, Richard, Tachedjian, Gilda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743514/ https://www.ncbi.nlm.nih.gov/pubmed/23657804 http://dx.doi.org/10.1093/jac/dkt156 |
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