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Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis

Inflammatory pseudotumor (IPT) is a benign entity that may present as a solid mass mimicking a malignant neoplasm. Histologically, they are composed of varying proportions of myofibroblastic spindle cells, lymphocytes, and plasma cells. Skull base IPT is rare and usually occurs in adults with no sex...

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Detalles Bibliográficos
Autores principales: Huang, Biao, Liu, Hong-Jun, Liang, Chang-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743602/
https://www.ncbi.nlm.nih.gov/pubmed/23984211
http://dx.doi.org/10.1055/s-0031-1280739
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author Huang, Biao
Liu, Hong-Jun
Liang, Chang-Hong
author_facet Huang, Biao
Liu, Hong-Jun
Liang, Chang-Hong
author_sort Huang, Biao
collection PubMed
description Inflammatory pseudotumor (IPT) is a benign entity that may present as a solid mass mimicking a malignant neoplasm. Histologically, they are composed of varying proportions of myofibroblastic spindle cells, lymphocytes, and plasma cells. Skull base IPT is rare and usually occurs in adults with no sex predilection. The skull base IPT typically presents with headache, and/or cranial nerve palsy. There is no consensus regarding treatment of skull base IPT due to its rarity. Surgical resection and corticosteroid therapy have generally been used. The preoperative diagnosis of skull base IPT is usually difficult due to its nonspecific clinical and radiologic features. We report a case of a 42-year-old woman with IPT originating from the skull base. To our knowledge, this is the first case of IPT invading fissura petrooccipitalis. When a mass in the skull base appears hypointense on T2-weighted imaging with aggressive growth and bony destruction, IPT should be considered in the differential diagnosis.
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spelling pubmed-37436022013-08-27 Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis Huang, Biao Liu, Hong-Jun Liang, Chang-Hong Skull Base Rep Article Inflammatory pseudotumor (IPT) is a benign entity that may present as a solid mass mimicking a malignant neoplasm. Histologically, they are composed of varying proportions of myofibroblastic spindle cells, lymphocytes, and plasma cells. Skull base IPT is rare and usually occurs in adults with no sex predilection. The skull base IPT typically presents with headache, and/or cranial nerve palsy. There is no consensus regarding treatment of skull base IPT due to its rarity. Surgical resection and corticosteroid therapy have generally been used. The preoperative diagnosis of skull base IPT is usually difficult due to its nonspecific clinical and radiologic features. We report a case of a 42-year-old woman with IPT originating from the skull base. To our knowledge, this is the first case of IPT invading fissura petrooccipitalis. When a mass in the skull base appears hypointense on T2-weighted imaging with aggressive growth and bony destruction, IPT should be considered in the differential diagnosis. Thieme Medical Publishers 2011-07-07 2011-11 /pmc/articles/PMC3743602/ /pubmed/23984211 http://dx.doi.org/10.1055/s-0031-1280739 Text en © Thieme Medical Publishers
spellingShingle Article
Huang, Biao
Liu, Hong-Jun
Liang, Chang-Hong
Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis
title Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis
title_full Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis
title_fullStr Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis
title_full_unstemmed Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis
title_short Inflammatory Pseudotumor of the Skull Base Involving Fissura Petrooccipitalis: A Rare Case with Challenging Diagnosis
title_sort inflammatory pseudotumor of the skull base involving fissura petrooccipitalis: a rare case with challenging diagnosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743602/
https://www.ncbi.nlm.nih.gov/pubmed/23984211
http://dx.doi.org/10.1055/s-0031-1280739
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