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Down-Regulation of C9orf86 in Human Breast Cancer Cells Inhibits Cell Proliferation, Invasion and Tumor Growth and Correlates with Survival of Breast Cancer Patients

C9orf86 which is a novel subfamily within the Ras superfamily of GTPases, is overexpressed in the majority of primary breast tumors. Few functional studies have focused on the C9orf86 protein; therefore, in this study, we explored the role of C9orf86 in breast carcinogenesis. In our study, we found...

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Detalles Bibliográficos
Autores principales: Li, Yang-Yang, Fu, Sha, Wang, Xiao-Pai, Wang, Hai-Yun, Zeng, Mu-Sheng, Shao, Jian-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743754/
https://www.ncbi.nlm.nih.gov/pubmed/23977139
http://dx.doi.org/10.1371/journal.pone.0071764