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Natural Haemozoin Induces Expression and Release of Human Monocyte Tissue Inhibitor of Metalloproteinase-1
Recently matrix metalloproteinase-9 (MMP-9) and its endogenous inhibitor (tissue inhibitor of metalloproteinase-1, TIMP-1) have been implicated in complicated malaria. In vivo, mice with cerebral malaria (CM) display high levels of both MMP-9 and TIMP-1, and in human patients TIMP-1 serum levels dir...
Autores principales: | Polimeni, Manuela, Valente, Elena, Ulliers, Daniela, Opdenakker, Ghislain, Van den Steen, Philippe E., Giribaldi, Giuliana, Prato, Mauro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743797/ https://www.ncbi.nlm.nih.gov/pubmed/23967215 http://dx.doi.org/10.1371/journal.pone.0071468 |
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