Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury

Experimental and clinical evidence point strongly toward the potential for microvascular stresses to influence the severity and expression of ventilator associated lung injury. Intense microvascular stresses not only influence edema but predispose to structural failure of the gas–blood barrier, poss...

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Detalles Bibliográficos
Autores principales: Marini, John J, Hotchkiss, John R, Broccard, Alain F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC374383/
https://www.ncbi.nlm.nih.gov/pubmed/14624683
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author Marini, John J
Hotchkiss, John R
Broccard, Alain F
author_facet Marini, John J
Hotchkiss, John R
Broccard, Alain F
author_sort Marini, John J
collection PubMed
description Experimental and clinical evidence point strongly toward the potential for microvascular stresses to influence the severity and expression of ventilator associated lung injury. Intense microvascular stresses not only influence edema but predispose to structural failure of the gas–blood barrier, possibly with adverse consequences for the lung and for extrapulmonary organs. Taking measures to lower vascular stress may offer a logical, but as yet unproven, extension of a lung-protective strategy for life support in ARDS.
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spelling pubmed-3743832004-03-25 Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury Marini, John J Hotchkiss, John R Broccard, Alain F Crit Care Review Experimental and clinical evidence point strongly toward the potential for microvascular stresses to influence the severity and expression of ventilator associated lung injury. Intense microvascular stresses not only influence edema but predispose to structural failure of the gas–blood barrier, possibly with adverse consequences for the lung and for extrapulmonary organs. Taking measures to lower vascular stress may offer a logical, but as yet unproven, extension of a lung-protective strategy for life support in ARDS. BioMed Central 2003 2003-10-17 /pmc/articles/PMC374383/ /pubmed/14624683 Text en Copyright © 2003 BioMed Central Ltd
spellingShingle Review
Marini, John J
Hotchkiss, John R
Broccard, Alain F
Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury
title Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury
title_full Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury
title_fullStr Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury
title_full_unstemmed Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury
title_short Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury
title_sort bench-to-bedside review: microvascular and airspace linkage in ventilator-induced lung injury
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC374383/
https://www.ncbi.nlm.nih.gov/pubmed/14624683
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AT hotchkissjohnr benchtobedsidereviewmicrovascularandairspacelinkageinventilatorinducedlunginjury
AT broccardalainf benchtobedsidereviewmicrovascularandairspacelinkageinventilatorinducedlunginjury

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