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The Prognostic Significance of IRF8 Transcripts in Adult Patients with Acute Myeloid Leukemia

Interferon regulatory factor 8 (IRF8) is a transcription factor that plays a critical role in normal hematopoiesis, such that disruption of IRF8 activity promotes leukemogenesis. We and others have identified aberrant expression of IRF8 transcripts, including novel splice variants, in acute myeloid...

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Detalles Bibliográficos
Autores principales: Pogosova-Agadjanyan, Era L., Kopecky, Kenneth J., Ostronoff, Fabiana, Appelbaum, Frederick R., Godwin, John, Lee, Hana, List, Alan F., May, Jennifer J., Oehler, Vivian G., Petersdorf, Steve, Pogosov, Galina L., Radich, Jerald P., Willman, Cheryl L., Meshinchi, Soheil, Stirewalt, Derek L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743845/
https://www.ncbi.nlm.nih.gov/pubmed/23967110
http://dx.doi.org/10.1371/journal.pone.0070812