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The Prognostic Significance of IRF8 Transcripts in Adult Patients with Acute Myeloid Leukemia
Interferon regulatory factor 8 (IRF8) is a transcription factor that plays a critical role in normal hematopoiesis, such that disruption of IRF8 activity promotes leukemogenesis. We and others have identified aberrant expression of IRF8 transcripts, including novel splice variants, in acute myeloid...
Autores principales: | Pogosova-Agadjanyan, Era L., Kopecky, Kenneth J., Ostronoff, Fabiana, Appelbaum, Frederick R., Godwin, John, Lee, Hana, List, Alan F., May, Jennifer J., Oehler, Vivian G., Petersdorf, Steve, Pogosov, Galina L., Radich, Jerald P., Willman, Cheryl L., Meshinchi, Soheil, Stirewalt, Derek L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743845/ https://www.ncbi.nlm.nih.gov/pubmed/23967110 http://dx.doi.org/10.1371/journal.pone.0070812 |
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