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Comparative Genomic Analysis of Brucella melitensis Vaccine Strain M5 Provides Insights into Virulence Attenuation

The Brucella melitensis vaccine strain M5 is widely used to prevent and control brucellosis in animals. In this study, we determined the whole-genome sequence of M5, and conducted a comprehensive comparative analysis against the whole-genome sequence of the virulent strain 16 M and other reference s...

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Detalles Bibliográficos
Autores principales: Jiang, Hai, Du, Pengcheng, Zhang, Wen, Wang, Heng, Zhao, Hongyan, Piao, Dongri, Tian, Guozhong, Chen, Chen, Cui, Buyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743847/
https://www.ncbi.nlm.nih.gov/pubmed/23967122
http://dx.doi.org/10.1371/journal.pone.0070852