Deep Tissue Injury in Development of Pressure Ulcers: A Decrease of Inflammasome Activation and Changes in Human Skin Morphology in Response to Aging and Mechanical Load

Molecular mechanisms leading to pressure ulcer development are scarce in spite of high mortality of patients. Development of pressure ulcers that is initially observed as deep tissue injury is multifactorial. We postulate that biomechanical forces and inflammasome activation, together with ischemia...

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Detalles Bibliográficos
Autores principales: Stojadinovic, Olivera, Minkiewicz, Julia, Sawaya, Andrew, Bourne, Jonathan W., Torzilli, Peter, de Rivero Vaccari, Juan Pablo, Dietrich, W. Dalton, Keane, Robert W., Tomic-Canic, Marjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743891/
https://www.ncbi.nlm.nih.gov/pubmed/23967056
http://dx.doi.org/10.1371/journal.pone.0069223

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