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Secretion of Protective Antigens by Tissue-Stage Nematode Larvae Revealed by Proteomic Analysis and Vaccination-Induced Sterile Immunity
Gastrointestinal nematode parasites infect over 1 billion humans, with little evidence for generation of sterilising immunity. These helminths are highly adapted to their mammalian host, following a developmental program through successive niches, while effectively down-modulating host immune respon...
Autores principales: | Hewitson, James P., Ivens, Al C., Harcus, Yvonne, Filbey, Kara J., McSorley, Henry J., Murray, Janice, Bridgett, Stephen, Ashford, David, Dowle, Adam A., Maizels, Rick M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744408/ https://www.ncbi.nlm.nih.gov/pubmed/23966853 http://dx.doi.org/10.1371/journal.ppat.1003492 |
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