Introns Regulate Gene Expression in Cryptococcus neoformans in a Pab2p Dependent Pathway

Most Cryptococccus neoformans genes are interrupted by introns, and alternative splicing occurs very often. In this study, we examined the influence of introns on C. neoformans gene expression. For most tested genes, elimination of introns greatly reduces mRNA accumulation. Strikingly, the number an...

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Detalles Bibliográficos
Autores principales: Goebels, Carolin, Thonn, Aline, Gonzalez-Hilarion, Sara, Rolland, Olga, Moyrand, Frederique, Beilharz, Traude H., Janbon, Guilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744415/
https://www.ncbi.nlm.nih.gov/pubmed/23966870
http://dx.doi.org/10.1371/journal.pgen.1003686

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