A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes

GC-biased gene conversion (gBGC) is a recombination-associated process that favors the fixation of G/C alleles over A/T alleles. In mammals, gBGC is hypothesized to contribute to variation in GC content, rapidly evolving sequences, and the fixation of deleterious mutations, but its prevalence and ge...

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Detalles Bibliográficos
Autores principales: Capra, John A., Hubisz, Melissa J., Kostka, Dennis, Pollard, Katherine S., Siepel, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744432/
https://www.ncbi.nlm.nih.gov/pubmed/23966869
http://dx.doi.org/10.1371/journal.pgen.1003684

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