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Hypoxia-Inducible Factor-1α and Interleukin 33 Form a Regulatory Circuit to Perpetuate the Inflammation in Rheumatoid Arthritis
Hyperplasia of synovial fibroblasts, infiltration with inflammatory cytokines, and tissue hypoxia are the major characteristics of rheumatoid arthritis (RA). Interleukin 33 (IL-33) is a newly identified inflammatory cytokine exacerbating the disease severity of RA. Hypoxia-inducible factor-1α (HIF-1...
Autores principales: | Hu, Fanlei, Shi, Lianjie, Mu, Rong, Zhu, Jiaxin, Li, Yingni, Ma, Xiaoxu, Li, Chun, Jia, Rulin, Yang, Dongyue, Li, Yun, Li, Zhanguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744448/ https://www.ncbi.nlm.nih.gov/pubmed/23967327 http://dx.doi.org/10.1371/journal.pone.0072650 |
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