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Hypoxia-Inducible Factor-1α and Interleukin 33 Form a Regulatory Circuit to Perpetuate the Inflammation in Rheumatoid Arthritis

Hyperplasia of synovial fibroblasts, infiltration with inflammatory cytokines, and tissue hypoxia are the major characteristics of rheumatoid arthritis (RA). Interleukin 33 (IL-33) is a newly identified inflammatory cytokine exacerbating the disease severity of RA. Hypoxia-inducible factor-1α (HIF-1...

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Detalles Bibliográficos
Autores principales:	Hu, Fanlei, Shi, Lianjie, Mu, Rong, Zhu, Jiaxin, Li, Yingni, Ma, Xiaoxu, Li, Chun, Jia, Rulin, Yang, Dongyue, Li, Yun, Li, Zhanguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744448/ https://www.ncbi.nlm.nih.gov/pubmed/23967327 http://dx.doi.org/10.1371/journal.pone.0072650

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