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Evidence for a Crucial Role of Paneth Cells in Mediating the Intestinal Response to Injury

The identification of the intestinal stem cell (ISC) markers Lgr5 and Bmi-1 has furthered our understanding of how they accomplish homeostasis in this rapidly self-renewing tissue. Recent work indicates that these markers identify a cycling Lgr5(+) ISC which can be replaced by a quiescent Bmi-1(+) I...

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Detalles Bibliográficos
Autores principales:	Parry, Lee, Young, Madeleine, El Marjou, Fatima, Clarke, Alan R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Subscription Services, Inc., A Wiley Company 2013
Materias:	Tissue Specific Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744757/ https://www.ncbi.nlm.nih.gov/pubmed/23335179 http://dx.doi.org/10.1002/stem.1326

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