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DNA-dependent SUMO modification of PARP-1()

Poly(ADP-ribose) polymerase 1 (PARP-1) plays an important role in DNA repair, but also contributes to other aspects of nucleic acid metabolism, such as transcriptional regulation. Modification of PARP-1 with the small ubiquitin-related modifier (SUMO) affects its function as a transcriptional co-act...

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Detalles Bibliográficos
Autores principales: Zilio, Nicola, Williamson, Chris T., Eustermann, Sebastian, Shah, Rajvee, West, Stephen C., Neuhaus, David, Ulrich, Helle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744807/
https://www.ncbi.nlm.nih.gov/pubmed/23871147
http://dx.doi.org/10.1016/j.dnarep.2013.07.001