The PI3K/Akt1 pathway enhances steady-state levels of FANCL

Fanconi anemia hematopoietic stem cells display poor self-renewal capacity when subjected to a variety of cellular stress. This phenotype raises the question of whether the Fanconi anemia proteins are stabilized or recruited as part of a stress response and protect against stem cell loss. Here we pr...

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Detalles Bibliográficos
Autores principales: Dao, Kim-Hien T., Rotelli, Michael D., Brown, Brieanna R., Yates, Jane E., Rantala, Juha, Tognon, Cristina, Tyner, Jeffrey W., Druker, Brian J., Bagby, Grover C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744951/
https://www.ncbi.nlm.nih.gov/pubmed/23783032
http://dx.doi.org/10.1091/mbc.E13-03-0144

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