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A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm

Patient: Male, 59 Final Diagnosis: Xanthogranulomatous osteomyelitis Symptoms: Painful swelling in the wrist Medication: Drug history of antifulgal agents Clinical Procedure: Excisional biopsy Specialty: Radiology OBJECTIVE: Rare disease BACKGROUND: Xanthogranulomatous inflammation is a chronic infl...

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Detalles Bibliográficos
Autores principales: Lee, Seung Hyun, Lee, Young Han, Park, Heejung, Cho, Yong Jin, Song, Ho-Taek, Yang, Woo Ik, Suh, Jin-Suck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745271/
https://www.ncbi.nlm.nih.gov/pubmed/23961304
http://dx.doi.org/10.12659/AJCR.889422
Descripción
Sumario:Patient: Male, 59 Final Diagnosis: Xanthogranulomatous osteomyelitis Symptoms: Painful swelling in the wrist Medication: Drug history of antifulgal agents Clinical Procedure: Excisional biopsy Specialty: Radiology OBJECTIVE: Rare disease BACKGROUND: Xanthogranulomatous inflammation is a chronic inflammatory disease in which bone involvement is extremely rare. Bone involvement of xanthogranulomatous inflammation, termed xanthogranulomatous osteomyelitis (XO), often presents as a mass-like lesion extending to adjacent structures, which can mimic infiltrative carcinoma. CASE REPORT: We present a case of XO in the ulna, which mimicked a neoplasm. A 59-year-old man presented with a 2-month history of painful swelling in the right wrist. Plain radiography and CT showed an osteolytic lesion at the distal ulna. MRI revealed a soft-tissue mass with lobulated margins and contrast enhancement. Intense uptake in bone scan and PET suggested malignancy. An excisional biopsy from the representative area resulted in a pathology diagnosis of XO. CONCLUSIONS: Gross and radiologic manifestations of XO can mimic neoplasm. XO generally has benign prognosis, contrary to malignant bone tumor. Therefore, biopsy and histopathological confirmation are necessary for proper management.