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A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm

Patient: Male, 59 Final Diagnosis: Xanthogranulomatous osteomyelitis Symptoms: Painful swelling in the wrist Medication: Drug history of antifulgal agents Clinical Procedure: Excisional biopsy Specialty: Radiology OBJECTIVE: Rare disease BACKGROUND: Xanthogranulomatous inflammation is a chronic infl...

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Autores principales: Lee, Seung Hyun, Lee, Young Han, Park, Heejung, Cho, Yong Jin, Song, Ho-Taek, Yang, Woo Ik, Suh, Jin-Suck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745271/
https://www.ncbi.nlm.nih.gov/pubmed/23961304
http://dx.doi.org/10.12659/AJCR.889422
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author Lee, Seung Hyun
Lee, Young Han
Park, Heejung
Cho, Yong Jin
Song, Ho-Taek
Yang, Woo Ik
Suh, Jin-Suck
author_facet Lee, Seung Hyun
Lee, Young Han
Park, Heejung
Cho, Yong Jin
Song, Ho-Taek
Yang, Woo Ik
Suh, Jin-Suck
author_sort Lee, Seung Hyun
collection PubMed
description Patient: Male, 59 Final Diagnosis: Xanthogranulomatous osteomyelitis Symptoms: Painful swelling in the wrist Medication: Drug history of antifulgal agents Clinical Procedure: Excisional biopsy Specialty: Radiology OBJECTIVE: Rare disease BACKGROUND: Xanthogranulomatous inflammation is a chronic inflammatory disease in which bone involvement is extremely rare. Bone involvement of xanthogranulomatous inflammation, termed xanthogranulomatous osteomyelitis (XO), often presents as a mass-like lesion extending to adjacent structures, which can mimic infiltrative carcinoma. CASE REPORT: We present a case of XO in the ulna, which mimicked a neoplasm. A 59-year-old man presented with a 2-month history of painful swelling in the right wrist. Plain radiography and CT showed an osteolytic lesion at the distal ulna. MRI revealed a soft-tissue mass with lobulated margins and contrast enhancement. Intense uptake in bone scan and PET suggested malignancy. An excisional biopsy from the representative area resulted in a pathology diagnosis of XO. CONCLUSIONS: Gross and radiologic manifestations of XO can mimic neoplasm. XO generally has benign prognosis, contrary to malignant bone tumor. Therefore, biopsy and histopathological confirmation are necessary for proper management.
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spelling pubmed-37452712013-08-19 A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm Lee, Seung Hyun Lee, Young Han Park, Heejung Cho, Yong Jin Song, Ho-Taek Yang, Woo Ik Suh, Jin-Suck Am J Case Rep Articles Patient: Male, 59 Final Diagnosis: Xanthogranulomatous osteomyelitis Symptoms: Painful swelling in the wrist Medication: Drug history of antifulgal agents Clinical Procedure: Excisional biopsy Specialty: Radiology OBJECTIVE: Rare disease BACKGROUND: Xanthogranulomatous inflammation is a chronic inflammatory disease in which bone involvement is extremely rare. Bone involvement of xanthogranulomatous inflammation, termed xanthogranulomatous osteomyelitis (XO), often presents as a mass-like lesion extending to adjacent structures, which can mimic infiltrative carcinoma. CASE REPORT: We present a case of XO in the ulna, which mimicked a neoplasm. A 59-year-old man presented with a 2-month history of painful swelling in the right wrist. Plain radiography and CT showed an osteolytic lesion at the distal ulna. MRI revealed a soft-tissue mass with lobulated margins and contrast enhancement. Intense uptake in bone scan and PET suggested malignancy. An excisional biopsy from the representative area resulted in a pathology diagnosis of XO. CONCLUSIONS: Gross and radiologic manifestations of XO can mimic neoplasm. XO generally has benign prognosis, contrary to malignant bone tumor. Therefore, biopsy and histopathological confirmation are necessary for proper management. International Scientific Literature, Inc. 2013-08-09 /pmc/articles/PMC3745271/ /pubmed/23961304 http://dx.doi.org/10.12659/AJCR.889422 Text en © Am J Case Rep, 2013 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License
spellingShingle Articles
Lee, Seung Hyun
Lee, Young Han
Park, Heejung
Cho, Yong Jin
Song, Ho-Taek
Yang, Woo Ik
Suh, Jin-Suck
A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm
title A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm
title_full A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm
title_fullStr A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm
title_full_unstemmed A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm
title_short A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm
title_sort case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745271/
https://www.ncbi.nlm.nih.gov/pubmed/23961304
http://dx.doi.org/10.12659/AJCR.889422
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