Uroplakin Peptide-Specific Autoimmunity Initiates Interstitial Cystitis/Painful Bladder Syndrome in Mice

The pathophysiology of interstitial cystitis/painful bladder syndrome (IC/PBS) is enigmatic. Autoimmunity and impaired urothelium might lead the underlying pathology. A major shortcoming in IC/PBS research has been the lack of an appropriate animal model. In this study, we show that the bladder spec...

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Detalles Bibliográficos
Autores principales: Izgi, Kenan, Altuntas, Cengiz Z., Bicer, Fuat, Ozer, Ahmet, Sakalar, Cagri, Li, Xiaoxia, Tuohy, Vincent K., Daneshgari, Firouz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745386/
https://www.ncbi.nlm.nih.gov/pubmed/23977210
http://dx.doi.org/10.1371/journal.pone.0072067

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