Dopamine D1 Receptor Gene Variation Modulates Opioid Dependence Risk by Affecting Transition to Addiction

Dopamine D1 receptor (DRD1) modulates opioid reinforcement, reward, and opioid-induced neuroadaptation. We propose that DRD1 polymorphism affects susceptibility to opioid dependence (OD), the efficiency of transition to OD, and opioid-induced pleasure response. We analyzed potential association betw...

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Detalles Bibliográficos
Autores principales: Zhu, Feng, Yan, Chun-xia, Wen, Yi-chong, Wang, Jiayin, Bi, Jinbo, Zhao, Ya-ling, Wei, Lai, Gao, Cheng-ge, Jia, Wei, Li, Sheng-bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745389/
https://www.ncbi.nlm.nih.gov/pubmed/23976958
http://dx.doi.org/10.1371/journal.pone.0070805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745389/
https://www.ncbi.nlm.nih.gov/pubmed/23976958
http://dx.doi.org/10.1371/journal.pone.0070805

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