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Extinction of Hepatitis C Virus by Ribavirin in Hepatoma Cells Involves Lethal Mutagenesis

Lethal mutagenesis, or virus extinction produced by enhanced mutation rates, is under investigation as an antiviral strategy that aims at counteracting the adaptive capacity of viral quasispecies, and avoiding selection of antiviral-escape mutants. To explore lethal mutagenesis of hepatitis C virus...

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Detalles Bibliográficos
Autores principales:	Ortega-Prieto, Ana M., Sheldon, Julie, Grande-Pérez, Ana, Tejero, Héctor, Gregori, Josep, Quer, Josep, Esteban, Juan I., Domingo, Esteban, Perales, Celia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745404/ https://www.ncbi.nlm.nih.gov/pubmed/23976977 http://dx.doi.org/10.1371/journal.pone.0071039

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