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Sonic Hedgehog Carried by Microparticles Corrects Angiotensin II-Induced Hypertension and Endothelial Dysfunction in Mice
Microparticles are small fragments of the plasma membrane generated after cell stimulation. We recently showed that Sonic hedgehog (Shh) is present in microparticles generated from activated/apoptotic human T lymphocytes and corrects endothelial injury through nitric oxide (NO) release. This study i...
Autores principales: | Marrachelli, Vannina González, Mastronardi, Maria Letizia, Sarr, Mamadou, Soleti, Raffaella, Leonetti, Daniela, Martínez, María Carmen, Andriantsitohaina, Ramaroson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745429/ https://www.ncbi.nlm.nih.gov/pubmed/23977364 http://dx.doi.org/10.1371/journal.pone.0072861 |
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