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In Vitro Neutralization of Low Dose Inocula at Physiological Concentrations of a Monoclonal Antibody Which Protects Macaques against SHIV Challenge
BACKGROUND: Passive transfer of antibodies can be protective in the simian human immunodeficiency virus (SHIV) – rhesus macaque challenge model. The human monoclonal antibody IgG1 b12 neutralizes human immunodeficiency type 1 (HIV-1) in vitro and protects against challenge by SHIV. Our hypothesis is...
Autores principales: | Davis, David, Koornstra, Wim, Fagrouch, Zahra, Verschoor, Ernst J., Heeney, Jonathan L., Bogers, Willy M. J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745472/ https://www.ncbi.nlm.nih.gov/pubmed/23977339 http://dx.doi.org/10.1371/journal.pone.0072702 |
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