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Labeling and Biological Evaluation of (99m)Tc-HYNIC-Trastuzumab as a Potential Radiopharmaceutical for In Vivo Evaluation of HER2 Expression in Breast Cancer

The amplification of HER2 gene has been described in several tumor types, mainly breast cancer with a subsequent increase in HER2 protein expression. Trastuzumab is a humanized monoclonal antibody that recognizes selectively the HER2 extracellular domain. The objective of the present work was to sta...

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Detalles Bibliográficos
Autores principales:	Calzada, Victoria, Garcia, Fernanda, Fernández, Marcelo, Porcal, Williams, Quinn, Thomas, Alonso, Omar, Gambini, Juan Pablo, Cabral, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745630/ https://www.ncbi.nlm.nih.gov/pubmed/23961253 http://dx.doi.org/10.4103/1450-1147.113953

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