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Denosumab Chemotherapy for Recurrent Giant-Cell Tumor of Bone: A Case Report of Neoadjuvant Use Enabling Complete Surgical Resection

Giant-cell tumor of the bone (GCTB) is a rare neoplasm that affects young adults. The tumor is generally benign but sometimes can be locally aggressive. There are no standardized approaches to the treatment of GCTB. Recently, the RANKL inhibitor denosumab has shown activity in this tumor type. We pr...

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Detalles Bibliográficos
Autores principales: Agarwal, Amit, Larsen, Brandon T., Buadu, Lawrence D., Dunn, Jack, Crawford, Russell, Daniel, Jonathan, Bishop, Maria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745896/
https://www.ncbi.nlm.nih.gov/pubmed/23984138
http://dx.doi.org/10.1155/2013/496351