Cargando…

SOD1 and DJ-1 Converge at Nrf2 Pathway: A Clue for Antioxidant Therapeutic Potential in Neurodegeneration

Neurodegenerative diseases share diverse pathological features and among these oxidative stress (OS) plays a leading role. Impaired activity and reduced expression of antioxidant proteins have been reported as common events in several aging-associated disorders. In this review paper, we first provid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Milani, Pamela, Ambrosi, Giulia, Gammoh, Omar, Blandini, Fabio, Cereda, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745953/ https://www.ncbi.nlm.nih.gov/pubmed/23983902 http://dx.doi.org/10.1155/2013/836760

Ejemplares similares

SOD1 Transcriptional and Posttranscriptional Regulation and Its Potential Implications in ALS
por: Milani, Pamela, et al.
Publicado: (2011)

DJ-1 and SOD1 Act Independently in the Protection against Anoxia in Drosophila melanogaster
por: De Lazzari, Federica, et al.
Publicado: (2022)

Neurodevelopmental Clues to Neurodegeneration
por: Schor, Nina F., et al.
Publicado: (2021)

Salidroside Protects against MPP+-Induced Neuronal Injury through DJ-1-Nrf2 Antioxidant Pathway
por: Wu, Leitao, et al.
Publicado: (2017)

LINGO-1 and Neurodegeneration: Pathophysiologic Clues for Essential Tremor
por: Zhou, Zhi-dong, et al.
Publicado: (2012)

Salidroside Protects Dopaminergic Neurons by Preserving Complex I Activity via DJ-1/Nrf2-Mediated Antioxidant Pathway
por: Li, Ruru, et al.
Publicado: (2019)

AITC induces MRP1 expression by protecting against CS/CSE-mediated DJ-1 protein degradation via activation of the DJ-1/Nrf2 axis
por: Xu, Lingling, et al.
Publicado: (2020)

Altered Intracellular Localization of SOD1 in Leukocytes from Patients with Sporadic Amyotrophic Lateral Sclerosis
por: Cereda, Cristina, et al.
Publicado: (2013)

The Polg Mutator Phenotype Does Not Cause Dopaminergic Neurodegeneration in DJ-1-Deficient Mice1,2,3
por: Hauser, David N., et al.
Publicado: (2015)

Transcriptional Activation of the Cholecystokinin Gene by DJ-1 through Interaction of DJ-1 with RREB1 and the Effect of DJ-1 on the Cholecystokinin Level in Mice
por: Yamane, Takuya, et al.
Publicado: (2013)

DJ-1-Nrf2 axis is activated upon murine β-coronavirus infection in the CNS
por: Kundu, Soumya, et al.
Publicado: (2021)

Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis
por: Kim, Do-Kyun, et al.
Publicado: (2016)

The Parkinson’s Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration
por: Repici, Mariaelena, et al.
Publicado: (2018)

The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson’s disease
por: Zhao, Miao, et al.
Publicado: (2021)

AGEs and neurodegeneration: the Nrf2/glyoxalase-1 interaction
por: Mastrocola, Raffaella
Publicado: (2016)

Reintroduction of DJ-1 in Müller Cells Inhibits Retinal Degeneration in the DJ-1 Deficient Retina
por: Gharbi, Naouel, et al.
Publicado: (2021)

Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging
por: Zhu, Yuanfei, et al.
Publicado: (2019)

Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats
por: Kitamura, Yoshihisa, et al.
Publicado: (2011)

DJ-1 upregulates the Nrf2/GPX4 signal pathway to inhibit trophoblast ferroptosis in the pathogenesis of preeclampsia
por: Liao, Tingting, et al.
Publicado: (2022)

Monomer DJ-1 and Its N-Terminal Sequence Are Necessary for Mitochondrial Localization of DJ-1 Mutants
por: Maita, Chinatsu, et al.
Publicado: (2013)

Cross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for Cancer
por: Raninga, Prahlad V., et al.
Publicado: (2014)

BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity
por: Deeg, Sebastian, et al.
Publicado: (2010)

The role of DJ-1 in anti-apoptosis
por: Ren, Haigang, et al.
Publicado: (2012)

The Role of DJ-1 in the Pathogenesis of Endometriosis
por: Rai, Priyanka, et al.
Publicado: (2011)

Persulfidation of DJ-1: Mechanism and Consequences
por: Galardon, Erwan, et al.
Publicado: (2022)

Transcriptional Activation of Low-Density Lipoprotein Receptor Gene by DJ-1 and Effect of DJ-1 on Cholesterol Homeostasis
por: Yamaguchi, Shiori, et al.
Publicado: (2012)

BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage
por: Qin, Li-xia, et al.
Publicado: (2017)

Unraveling Parkinson’s Disease Neurodegeneration: Does Aging Hold the Clues?
por: Coleman, Colin, et al.
Publicado: (2022)

Following the Clues: Usefulness of Biomarkers of Neuroinflammation and Neurodegeneration in the Investigation of HTLV-1-Associated Myelopathy Progression
por: Souza, Flávia dos Santos, et al.
Publicado: (2021)

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone
por: Torrente, Laura, et al.
Publicado: (2020)

SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease
por: Pansarasa, Orietta, et al.
Publicado: (2018)

Serum DJ-1 Is a Biomarker of Colorectal Cancer and DJ-1 Activates Mitophagy to Promote Colorectal Cancer Progression
por: Chen, William Tzu-Liang, et al.
Publicado: (2021)

A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2
por: Lev, Nirit, et al.
Publicado: (2015)

Mechanism of myocardial ischemia/reperfusion-induced acute kidney injury through DJ-1/Nrf2 pathway in diabetic rats
por: Sun, Qian, et al.
Publicado: (2017)

Cardioprotective effects of Cu((II))ATSM in human vascular smooth muscle cells and cardiomyocytes mediated by Nrf2 and DJ-1
por: Srivastava, Salil, et al.
Publicado: (2016)

DJ-1 protects retinal pericytes against high glucose-induced oxidative stress through the Nrf2 signaling pathway
por: Wang, Wanpeng, et al.
Publicado: (2020)

DJ-1 affects oxidative stress and pyroptosis in hippocampal neurons of Alzheimer's disease mouse model by regulating the Nrf2 pathway
por: Cheng, Lin, et al.
Publicado: (2021)

Neuroprotective Function of DJ-1 in Parkinson's Disease
por: Ariga, Hiroyoshi, et al.
Publicado: (2013)

DJ-1 in Ocular Diseases: A Review
por: Liu, Cong, et al.
Publicado: (2018)

DJ-1 as a Modulator of Autophagy: An Hypothesis
por: González-Polo, Rosa A., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tbt0a83uio1sccvncbqnfpre3d