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Transmission Model of Hepatitis B Virus with the Migration Effect
Hepatitis B is a globally infectious disease. Mathematical modeling of HBV transmission is an interesting research area. In this paper, we present characteristics of HBV virus transmission in the form of a mathematical model. We analyzed the effect of immigrants in the model to study the effect of i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745994/ https://www.ncbi.nlm.nih.gov/pubmed/23984318 http://dx.doi.org/10.1155/2013/150681 |
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author | Khan, Muhammad Altaf Islam, Saeed Arif, Muhammad ul Haq, Zahoor |
author_facet | Khan, Muhammad Altaf Islam, Saeed Arif, Muhammad ul Haq, Zahoor |
author_sort | Khan, Muhammad Altaf |
collection | PubMed |
description | Hepatitis B is a globally infectious disease. Mathematical modeling of HBV transmission is an interesting research area. In this paper, we present characteristics of HBV virus transmission in the form of a mathematical model. We analyzed the effect of immigrants in the model to study the effect of immigrants for the host population. We added the following flow parameters: “the transmission between migrated and exposed class” and “the transmission between migrated and acute class.” With these new features, we obtained a compartment model of six differential equations. First, we find the basic threshold quantity Ro and then find the local asymptotic stability of disease-free equilibrium and endemic equilibrium. Furthermore, we find the global stability of the disease-free and endemic equilibria. Previous similar publications have not added the kind of information about the numerical results of the model. In our case, from numerical simulation, a detailed discussion of the parameters and their numerical results is presented. We claim that with these assumptions and by adding the migrated class, the model informs policy for governments, to be aware of the immigrants and subject them to tests about the disease status. Immigrants for short visits and students should be subjected to tests to reduce the number of immigrants with disease. |
format | Online Article Text |
id | pubmed-3745994 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37459942013-08-27 Transmission Model of Hepatitis B Virus with the Migration Effect Khan, Muhammad Altaf Islam, Saeed Arif, Muhammad ul Haq, Zahoor Biomed Res Int Research Article Hepatitis B is a globally infectious disease. Mathematical modeling of HBV transmission is an interesting research area. In this paper, we present characteristics of HBV virus transmission in the form of a mathematical model. We analyzed the effect of immigrants in the model to study the effect of immigrants for the host population. We added the following flow parameters: “the transmission between migrated and exposed class” and “the transmission between migrated and acute class.” With these new features, we obtained a compartment model of six differential equations. First, we find the basic threshold quantity Ro and then find the local asymptotic stability of disease-free equilibrium and endemic equilibrium. Furthermore, we find the global stability of the disease-free and endemic equilibria. Previous similar publications have not added the kind of information about the numerical results of the model. In our case, from numerical simulation, a detailed discussion of the parameters and their numerical results is presented. We claim that with these assumptions and by adding the migrated class, the model informs policy for governments, to be aware of the immigrants and subject them to tests about the disease status. Immigrants for short visits and students should be subjected to tests to reduce the number of immigrants with disease. Hindawi Publishing Corporation 2013 2013-06-24 /pmc/articles/PMC3745994/ /pubmed/23984318 http://dx.doi.org/10.1155/2013/150681 Text en Copyright © 2013 Muhammad Altaf Khan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Khan, Muhammad Altaf Islam, Saeed Arif, Muhammad ul Haq, Zahoor Transmission Model of Hepatitis B Virus with the Migration Effect |
title | Transmission Model of Hepatitis B Virus with the Migration Effect |
title_full | Transmission Model of Hepatitis B Virus with the Migration Effect |
title_fullStr | Transmission Model of Hepatitis B Virus with the Migration Effect |
title_full_unstemmed | Transmission Model of Hepatitis B Virus with the Migration Effect |
title_short | Transmission Model of Hepatitis B Virus with the Migration Effect |
title_sort | transmission model of hepatitis b virus with the migration effect |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745994/ https://www.ncbi.nlm.nih.gov/pubmed/23984318 http://dx.doi.org/10.1155/2013/150681 |
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