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Transmission Model of Hepatitis B Virus with the Migration Effect

Hepatitis B is a globally infectious disease. Mathematical modeling of HBV transmission is an interesting research area. In this paper, we present characteristics of HBV virus transmission in the form of a mathematical model. We analyzed the effect of immigrants in the model to study the effect of i...

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Autores principales: Khan, Muhammad Altaf, Islam, Saeed, Arif, Muhammad, ul Haq, Zahoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745994/
https://www.ncbi.nlm.nih.gov/pubmed/23984318
http://dx.doi.org/10.1155/2013/150681
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author Khan, Muhammad Altaf
Islam, Saeed
Arif, Muhammad
ul Haq, Zahoor
author_facet Khan, Muhammad Altaf
Islam, Saeed
Arif, Muhammad
ul Haq, Zahoor
author_sort Khan, Muhammad Altaf
collection PubMed
description Hepatitis B is a globally infectious disease. Mathematical modeling of HBV transmission is an interesting research area. In this paper, we present characteristics of HBV virus transmission in the form of a mathematical model. We analyzed the effect of immigrants in the model to study the effect of immigrants for the host population. We added the following flow parameters: “the transmission between migrated and exposed class” and “the transmission between migrated and acute class.” With these new features, we obtained a compartment model of six differential equations. First, we find the basic threshold quantity Ro and then find the local asymptotic stability of disease-free equilibrium and endemic equilibrium. Furthermore, we find the global stability of the disease-free and endemic equilibria. Previous similar publications have not added the kind of information about the numerical results of the model. In our case, from numerical simulation, a detailed discussion of the parameters and their numerical results is presented. We claim that with these assumptions and by adding the migrated class, the model informs policy for governments, to be aware of the immigrants and subject them to tests about the disease status. Immigrants for short visits and students should be subjected to tests to reduce the number of immigrants with disease.
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spelling pubmed-37459942013-08-27 Transmission Model of Hepatitis B Virus with the Migration Effect Khan, Muhammad Altaf Islam, Saeed Arif, Muhammad ul Haq, Zahoor Biomed Res Int Research Article Hepatitis B is a globally infectious disease. Mathematical modeling of HBV transmission is an interesting research area. In this paper, we present characteristics of HBV virus transmission in the form of a mathematical model. We analyzed the effect of immigrants in the model to study the effect of immigrants for the host population. We added the following flow parameters: “the transmission between migrated and exposed class” and “the transmission between migrated and acute class.” With these new features, we obtained a compartment model of six differential equations. First, we find the basic threshold quantity Ro and then find the local asymptotic stability of disease-free equilibrium and endemic equilibrium. Furthermore, we find the global stability of the disease-free and endemic equilibria. Previous similar publications have not added the kind of information about the numerical results of the model. In our case, from numerical simulation, a detailed discussion of the parameters and their numerical results is presented. We claim that with these assumptions and by adding the migrated class, the model informs policy for governments, to be aware of the immigrants and subject them to tests about the disease status. Immigrants for short visits and students should be subjected to tests to reduce the number of immigrants with disease. Hindawi Publishing Corporation 2013 2013-06-24 /pmc/articles/PMC3745994/ /pubmed/23984318 http://dx.doi.org/10.1155/2013/150681 Text en Copyright © 2013 Muhammad Altaf Khan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Khan, Muhammad Altaf
Islam, Saeed
Arif, Muhammad
ul Haq, Zahoor
Transmission Model of Hepatitis B Virus with the Migration Effect
title Transmission Model of Hepatitis B Virus with the Migration Effect
title_full Transmission Model of Hepatitis B Virus with the Migration Effect
title_fullStr Transmission Model of Hepatitis B Virus with the Migration Effect
title_full_unstemmed Transmission Model of Hepatitis B Virus with the Migration Effect
title_short Transmission Model of Hepatitis B Virus with the Migration Effect
title_sort transmission model of hepatitis b virus with the migration effect
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745994/
https://www.ncbi.nlm.nih.gov/pubmed/23984318
http://dx.doi.org/10.1155/2013/150681
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