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Prefrontal Hypoactivity Associated with Impaired Inhibition in Stimulant-Dependent Individuals but Evidence for Hyperactivation in their Unaffected Siblings

A neurocognitive endophenotype has been proposed for stimulant dependence, based on behavioral measures of inhibitory response control associated with white matter changes in the frontal cortex. This study investigated the functional neuroimaging correlates of inhibitory response control, as functio...

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Detalles Bibliográficos
Autores principales: Morein-Zamir, Sharon, Simon Jones, P, Bullmore, Edward T, Robbins, Trevor W, Ersche, Karen D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746700/
https://www.ncbi.nlm.nih.gov/pubmed/23609131
http://dx.doi.org/10.1038/npp.2013.90