Process optimization and evaluation of novel baicalin solid nanocrystals

The objective of this study was to prepare baicalin solid nanocrystals (BCN-SNS) to enhance oral bioavailability of baicalin. A Box–Behnken design approach was used for process optimization. The physicochemical properties and pharmacokinetics of the optimal BCN-SNS were investigated. Multiple linear...

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Detalles Bibliográficos
Autores principales: Yue, Peng-Fei, Li, Yu, Wan, Jing, Wang, Yong, Yang, Ming, Zhu, Wei-Feng, Wang, Chang-Hong, Yuan, Hai-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746734/
https://www.ncbi.nlm.nih.gov/pubmed/23976849
http://dx.doi.org/10.2147/IJN.S44924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746734/
https://www.ncbi.nlm.nih.gov/pubmed/23976849
http://dx.doi.org/10.2147/IJN.S44924

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