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N-Palmitoylethanolamine depot injection increased its tissue levels and those of other acylethanolamide lipids
N-Palmitoylethanolamine (NAE 16:0) is an endogenous lipid signaling molecule that has limited water solubility, and its action is short-lived due to its rapid metabolism. This poses a problem for use in vivo as oral administration requires a high concentration for significant levels to reach target...
Autores principales: | Grillo, Stephanie L, Keereetaweep, Jantana, Grillo, Michael A, Chapman, Kent D, Koulen, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746786/ https://www.ncbi.nlm.nih.gov/pubmed/23976843 http://dx.doi.org/10.2147/DDDT.S48324 |
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