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The Amyloid Precursor Protein (APP) Does Not Have a Ferroxidase Site in Its E2 Domain

The ubiquitous 24-meric iron-storage protein ferritin and multicopper oxidases such as ceruloplasmin or hephaestin catalyze oxidation of Fe(II) to Fe(III), using molecular oxygen as oxidant. The ferroxidase activity of these proteins is essential for cellular iron homeostasis. It has been reported t...

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Detalles Bibliográficos
Autores principales:	Honarmand Ebrahimi, Kourosh, Dienemann, Christian, Hoefgen, Sandra, Than, Manuel E., Hagedoorn, Peter-Leon, Hagen, Wilfred R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747053/ https://www.ncbi.nlm.nih.gov/pubmed/23977245 http://dx.doi.org/10.1371/journal.pone.0072177

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