Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes

BACKGROUND: Podocytes serve as an important constituent of the glomerular filtration barrier. Recently, we and others identified Myo1e as a key molecular component of the podocyte cytoskeleton. RESULTS: Myo1e mRNA and protein was expressed in human and mouse kidney sections as determined by Northern...

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Detalles Bibliográficos
Autores principales: Mao, Jianhua, Wang, Dayan, Mataleena, Parikka, He, Bing, Niu, Dadi, Katayama, Kan, Xu, Xiangjun, Ojala, Juha RM, Wang, Wenjing, Shu, Qiang, Du, Lizhong, Liu, Aimin, Pikkarainen, Timo, Patrakka, Jaakko, Tryggvason, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747079/
https://www.ncbi.nlm.nih.gov/pubmed/23977349
http://dx.doi.org/10.1371/journal.pone.0072750

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