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Low ABCB1 Gene Expression Is an Early Event in Colorectal Carcinogenesis

The ABCB1/MDR1 gene product ABCB1/P-glycoprotein is implicated in the development of colorectal cancer (CRC). NFKB1 encodes transcription factors regulating expression of a number of genes including ABCB1. We have previously found association between the ABCB1 C-rs3789243-T polymorphism and CRC risk...

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Detalles Bibliográficos
Autores principales:	Andersen, Vibeke, Vogel, Ulla, Godiksen, Sine, Frenzel, Franz B., Sæbø, Mona, Hamfjord, Julian, Kure, Elin, Vogel, Lotte K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747088/ https://www.ncbi.nlm.nih.gov/pubmed/23977225 http://dx.doi.org/10.1371/journal.pone.0072119

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