Effect of Doxorubicin/Pluronic SP1049C on Tumorigenicity, Aggressiveness, DNA Methylation and Stem Cell Markers in Murine Leukemia

PURPOSE: Pluronic block copolymers are potent sensitizers of multidrug resistant cancers. SP1049C, a Pluronic-based micellar formulation of doxorubicin (Dox) has completed Phase II clinical trial and demonstrated safety and efficacy in patients with advanced adenocarcinoma of the esophagus and gastr...

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Detalles Bibliográficos
Autores principales: Alakhova, Daria Y., Zhao, Yi, Li, Shu, Kabanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747131/
https://www.ncbi.nlm.nih.gov/pubmed/23977261
http://dx.doi.org/10.1371/journal.pone.0072238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747131/
https://www.ncbi.nlm.nih.gov/pubmed/23977261
http://dx.doi.org/10.1371/journal.pone.0072238

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