Cargando…

Effect of Doxorubicin/Pluronic SP1049C on Tumorigenicity, Aggressiveness, DNA Methylation and Stem Cell Markers in Murine Leukemia

PURPOSE: Pluronic block copolymers are potent sensitizers of multidrug resistant cancers. SP1049C, a Pluronic-based micellar formulation of doxorubicin (Dox) has completed Phase II clinical trial and demonstrated safety and efficacy in patients with advanced adenocarcinoma of the esophagus and gastr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alakhova, Daria Y., Zhao, Yi, Li, Shu, Kabanov, Alexander V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747131/ https://www.ncbi.nlm.nih.gov/pubmed/23977261 http://dx.doi.org/10.1371/journal.pone.0072238

Ejemplares similares

Pluronics and MDR Reversal: An Update
por: Alakhova, Daria Y., et al.
Publicado: (2014)

Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer
por: Danson, S, et al.
Publicado: (2004)

Differentiation of human stem cells is promoted by amphiphilic pluronic block copolymers
por: Doğan, Ayşegül, et al.
Publicado: (2012)

Synthesis of Well-Defined Gold Nanoparticles Using Pluronic: The Role of Radicals and Surfactants in Nanoparticles Formation
por: Sokolsky-Papkov, Marina, et al.
Publicado: (2019)

Complete Sequence and Annotation of the Mycoplasma phocicerebrale Strain 1049(T) Genome
por: Frasca, Salvatore, et al.
Publicado: (2019)

Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers
por: Mahajan, Vivek, et al.
Publicado: (2016)

P1049: CHARACTERISTICS AND OUTCOMES OF CARDIOVASCULAR INVOLVEMENT IN ERDHEIM-CHESTER DISEASE
por: Tawfiq, Reema, et al.
Publicado: (2023)

Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion
por: Batrakova, E V, et al.
Publicado: (2001)

c(RGDyK)-decorated Pluronic micelles for enhanced doxorubicin and paclitaxel delivery to brain glioma
por: Huang, YuKun, et al.
Publicado: (2016)

c(RGDyK)-Decorated Pluronic Micelles for Enhanced Doxorubicin and Paclitaxel Delivery to Brain Glioma [Retraction]
Publicado: (2022)

Modification of Diet to Reduce the Stemness and Tumorigenicity of Murine and Human Intestinal Cells
por: May, Stephanie, et al.
Publicado: (2022)

Prevalence of positive urine culture in the presence of inactive urine sediment in 1049 urine samples from dogs
por: Strachan, Nicole A., et al.
Publicado: (2022)

PO-1049 COVID-19 pandemic impact on psychological state and care of cancer patients undergoing radiotherapy
por: Gasparini, L., et al.
Publicado: (2022)

Sa1049: IMPACT OF THE NOVEL COVID-19 VIRUS ON OUTCOMES OF GASTROINTESTINAL BLEEDING: A MULTICENTER STUDY
por: Chouhan, Vijit, et al.
Publicado: (2022)

Co-delivery of doxorubicin and itraconazole by Pluronic® P123 coated liposomes to enhance the anticancer effect in breast cancers
por: Lin, Yi, et al.
Publicado: (2018)

Characterization of protein marker expression, tumorigenicity, and doxorubicin chemoresistance in two new canine mammary tumor cell lines
por: Hsiao, Yen-Ling, et al.
Publicado: (2014)

Environmental and occupational respiratory diseases – 1049. Impacts of air pollution and enviornmental tobacco smoking on the symptoms of childhood asthma
por: Sim, Chang Sun, et al.
Publicado: (2013)

1049. Using Alternative Alerts in the Electronic Health Record to Guide Antimicrobial Selection Decisionmaking at the Point of Order Entry
por: Ebert, Steven C
Publicado: (2019)

Genome-Based Analysis of a Sequence Type 1049 Hypervirulent Klebsiella pneumoniae Causing Bacteremic Neck Abscess
por: Lan, Peng, et al.
Publicado: (2021)

Tumorigenic role of Musashi-2 in aggressive mantle cell lymphoma
por: Sureda-Gómez, Marta, et al.
Publicado: (2022)

Valproic Acid Prodrug Affects Selective Markers, Augments Doxorubicin Anticancer Activity and Attenuates Its Toxicity in a Murine Model of Aggressive Breast Cancer
por: Tarasenko, Nataly, et al.
Publicado: (2021)

Cardiovascular Aggression by Doxorubicin: The Search for Mechanisms
por: Martins, Wolney de Andrade
Publicado: (2018)

1049 Evaluating the Population Impact of HPV Vaccine on High Grade Cervical Intraepithelial Neoplasia Rates in an Era of Decreasing Screening
por: Patel, Deven, et al.
Publicado: (2014)

1049. Weight Gain in Persons Living with HIV (PLWH) Treated with Bictegravir Compared to Other Integrase Strand Transfer Inhibitors
por: Fang, Michelle, et al.
Publicado: (2020)

SG-APSIC1049: Immunogenicity of Gam-COVID-Vac and Sinopharm BBIBP-CorV vaccines in seropositive and seronegative adults
por: Stoma, Igor, et al.
Publicado: (2023)

In Vivo Biodistribution and Anti-Tumor Efficacy Evaluation of Doxorubicin and Paclitaxel-Loaded Pluronic Micelles Decorated with c(RGDyK) Peptide
por: Chen, Yanzuo, et al.
Publicado: (2016)

Pluronic P123 modified nano micelles loaded with doxorubicin enhanced tumor-suppressing effect on drug-resistant breast cancer cells
por: Zhang, Xiaoyu, et al.
Publicado: (2020)

Role of Lamin A/C as Candidate Biomarker of Aggressiveness and Tumorigenicity in Glioblastoma Multiforme
por: Gatti, Giuliana, et al.
Publicado: (2021)

Growth and transplantability of clonally related tumorigenic murine cell lines.
por: Walker, J. R.
Publicado: (1978)

1049. Outcome and Impact of Empirical Antimicrobial Treatment in Bacteraemia With Bacteroides Species; A Retrospective Cohort Study in a Region of Southern Sweden
por: Tham, Johan, et al.
Publicado: (2018)

Functional interaction between bases C1049 in domain II and G2751 in domain VI of 23S rRNA in Escherichia coli ribosomes
por: Miyoshi, Tomohiro, et al.
Publicado: (2008)

Rhizobium tumorigenes sp. nov., a novel plant tumorigenic bacterium isolated from cane gall tumors on thornless blackberry
por: Kuzmanović, Nemanja, et al.
Publicado: (2018)

Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus
por: Spring, Jessica, et al.
Publicado: (2022)

Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion
por: Zhong, Zhenyu, et al.
Publicado: (2018)

A clioquinol-containing Pluronic(®) F127 polymeric micelle system is effective in the treatment of visceral leishmaniasis in a murine model
por: Tavares, Grasiele S.V., et al.
Publicado: (2020)

Topical Delivery of Flurbiprofen from Pluronic Lecithin Organogel
por: Pandey, M. S., et al.
Publicado: (2009)

EPNs Exhibit Repulsion to Prenol in Pluronic Gel Assays
por: Baiocchi, Tiffany, et al.
Publicado: (2020)

Restoration of doxorubicin responsiveness in doxorubicin-resistant P388 murine leukaemia cells.
por: Ramu, A., et al.
Publicado: (1984)

Solutol(®)HS15+pluronicF127 and Solutol(®)HS15+pluronicL61 mixed micelle systems for oral delivery of genistein
por: Ding, Pinggang, et al.
Publicado: (2019)

Development of Doxorubicin-Loaded Magnetic Silica–Pluronic F-127 Nanocarriers Conjugated with Transferrin for Treating Glioblastoma across the Blood–Brain Barrier Using an in Vitro Model
por: Heggannavar, Geetha B., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ih5okve4l37iflsnf1uk7k2coe